时间：2019年11月8日（周五）中午12点30分
地点：卫津路校区教职工文化活动中心多功能厅
报告题目：肿瘤与蛋白质组学
主讲人：陈瑞冰
【个人简介】
陈瑞冰，天津大学药物科学与技术学院教授。2005年毕业于北京大学化学与分子工程学院获得学士学位。2009年毕业于美国威斯康星大学麦迪逊分校获博士学位。主要研究方向是肿瘤蛋白质组学。曾获天津市“131”人才第二层次、天津市青年科技优秀人才、天津市青年人才托举工程等人才称号。目前已发表SCI收录学术论文四十篇，其中第一/通讯作者论文21篇，多篇论文发表在组学领域国际高水平期刊Nucleic Acids Research和 Molecular & Cellular Proteomics上。作为项目负责人主持国家重点研发计划子课题及国家自然科学基金面上项目等4项国家级项目，并主持天津市自然科学基金等省部级科研项目5项。现任中国质谱学会理事，及多个国际期刊审稿人。
【报告内容简介】
癌症是来源于上皮细胞的恶性肿瘤，是严重影响人类健康的重大疾病。与正常细胞相比，肿瘤细胞获得了一系列特殊的生物学特性，例如持续增殖的能力、抗凋亡、激活血管生成、向周边组织浸润及发生转移。这些特性与肿瘤细胞内部生命过程的变化密不可分，这包括基因组的不稳定性、细胞代谢的改变以及炎症等等。蛋白质组学是近二十年快速发展起来的分子生物学检测技术，是高通量、定性、定量检测蛋白质分子及其化学修饰的重要方法，为我们了解肿瘤发生发展的调控机制、寻找新的治疗肿瘤的有效手段提供了必要手段。本报告将介绍癌症的生物学特征，简述调控肿瘤进展的重要生理过程，进而介绍蛋白质组学技术的发展及其在探索肿瘤发生发展机制及临床诊疗方面的应用和研究进展。
【相关学科】生命科学、医学、化学
【主办单位】校工会、图书馆、科研院、校青年教师联谊会
Lecture: Cancer and Proteomics
When: 12:30 p.m., Friday, November, 8th, 2019
Where: Multifunctional Hall, Cultural Activity Center for Faculty and Staff, Weijin Road Campus
Lecturer: Ruibing Chen
Ruibing Chen is a Professor at School of Pharmaceutical Science and Technology of Tianjin University. She graduated from Peking University in 2005, and obtained her PhD in Analytical Chemistry from University of Wisconsin at Madison in 2009. Research in her laboratory is focused on developing and implementing proteomics strategies to gain new insights into the molecular mechanisms regulating tumor development and progression. She has published 40 peer-reviewed scientific papers in top journals in the area of proteomics. She is now a committee member of the Chinese Society for Mass Spectrometry, and she serves as a reviewer for many international journals.
About the Lecture:
When normal cells evolve progressively to a neoplastic state, they acquire a succession of many hallmark capabilities, such as sustaining proliferative signaling, evading growth suppressors, resisting cell death, activating invasion and metastasis, etc. To better understand cancer biology is crucial to discover novel therapeutic anti-cancer strategies. Herein, I will firstly introduce these hallmarks of cancer, and then highlight the current progress in proteomics, and how we use proteomics strategies to study the mechanism and clinical phenotypes of cancer.
Relevant Discipline: life science, medical science, chemistry
Organizers: Trade Unions, Library, Office of Science and Technology, Young Teachers Association
All students and staff of Tianjin University are welcome.